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I would say just find a destination that really appeals to you and go for it. You will meet like minded people on whichever one you choose and almost certainly some will be doing their first trip too. My first JY holiday was 5 years ago to India. That was a pretty big one to start with but I absolutely loved it and since then have been on quite a few more both far and near, all of which have been great. I'm off to on the Kenyan Safari in 2 weeks and can't wait.
So book whatever really takes your fancy you'll be fine!
Best wishes Sue